AtlasVerify

Validate Tissue Quality Before Spatial Profiling

Derisk Spatial Assays with Sample Qualification

A high-throughput in-situ bulk qualification assay on an adjacent section helps predict spatial assay performance before you commit your slides.

Sample qualification in three steps

Prepare slides

Mount 5–10 µm sections on standard 1" × 3" slides (typically ~5 slides per sample), then ship to AtlasXomics.

In-situ qualification

We run an in-situ bulk qualification assay, generate an NGS library trace, and perform shallow sequencing (30–50M reads).

Evaluate performance

Review in-situ bulk peak signals (e.g., TSS enrichment, FRiP) to predict spatial performance on adjacent sections.

Why it matters: Spatial assays are expensive—sample qualification helps reduce failure risk from suboptimal blocks and increases confidence before scaling to full spatial profiling.

In-situ Bulk Qualification Assays Derisk Your Spatial Studies

Learn how a simple qualification workflow can flag challenging FFPE blocks early, guide ROI selection, and help you move forward with confidence.

Download white paper Discuss your samples

This qualification quickly answers:

  • Will this tissue work for spatial ATAC?
  • Is permeabilization optimal?
  • Is chromatin quality sufficient in this section?

Contact Us

Have questions or interested in collaborating? We’d love to hear from you.

Get in Touch ↗