Four steps from tissue to multi-omic spatial atlas
Built on DBiT-seq microfluidics and the AtlasXomics FlowGel platform. No specialized instruments required — works with your existing fluorescence microscope.
ATAC Tagmentation
Tn5 transposase fragments accessible chromatin in situ on the tissue section.
RNA Capture
Whole-transcriptome capture via random hexamer priming — not 3′-biased, providing uniform gene body coverage.
Spatial X-Barcoding
Microfluidic channels deliver unique DNA barcodes along the X-axis of the tissue grid.
Spatial Y-Barcoding
Perpendicular barcoding on the Y-axis completes the pixel grid, enabling coordinate-level readout.
True Multi-Omic Co-Detection
ATAC and RNA from the same tissue section — no serial sections or computational integration artifacts.
Whole-Transcriptome Capture
Random hexamer priming provides uniform gene body coverage, avoiding poly-A 3′ bias.
Regulatory State Discovery
Identify poised chromatin, temporal decoupling, and discordant regulation invisible to expression-only approaches.