
AtlasXomics Blog
Fresh insights from the spatial epigenome

EpiTrace: A Chromatin Clock to Map Cell Mitotic Age from scATAC‑seq
EpiTrace turns chromatin accessibility into a “clock,” letting scientists read how many times a cell has divided directly from single-cell ATAC-seq. Trained on ~126 k clock-like loci, the method accurately orders cells by mitotic age across embryos, organoids, and tumors—unlocking barcode-free lineage tracing and spatial maps of cellular aging.